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Depression Glossary

Remission and recovery in depression

Remission means a significant reduction of depressive symptoms to a minimal level — not the total absence of symptoms, but functioning close to normal. Clinically, it is defined as a low score on standardized scales (such as PHQ-9 <5) sustained for at least a few weeks.

Recovery is the maintenance of remission over a longer period (usually 6 months or more) — indicating that the depressive episode has passed. It differs from "cure," because depression tends to recur.

Why treating all the way to full remission matters: incomplete remission (residual symptoms) is the biggest risk factor for relapse and for more severe future episodes. Continuing treatment even after feeling better is crucial — stopping early roughly triples the risk of relapse.

Relapse prevention includes: continuing the antidepressant for the recommended length of time, maintenance psychotherapy, early recognition of warning signs, and lifestyle strategies (exercise, sleep, stress management).

Practical example

After two months of treatment, Paulo was "a lot better" — but his psychiatrist explained that "a lot better" isn't the same as full remission. There were still residual symptoms of insomnia and poor concentration. They kept him on the antidepressant for another six months after full remission — preventing the relapse that would likely occur if he stopped too soon.

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