SSRIs — Selective Serotonin Reuptake Inhibitors
SSRIs (Selective Serotonin Reuptake Inhibitors) are the most commonly prescribed class of antidepressants for anxiety disorders and depression. They work by blocking the reuptake of serotonin in the synaptic cleft, increasing the availability of this neurotransmitter. Examples: fluoxetine (Prozac), sertraline (Zoloft), escitalopram, paroxetine, fluvoxamine.
Despite the name 'antidepressant,' SSRIs are effective for all the major anxiety disorders: GAD, panic disorder, social phobia, OCD, and PTSD. They are the first-line pharmacotherapy for these conditions. Full therapeutic effects take 4-8 weeks to appear, and side effects (nausea, insomnia, sexual dysfunction) often improve over time.
They are not addictive in the classic pharmacological sense, but stopping them abruptly can cause discontinuation syndrome — so they should be tapered gradually under medical guidance.
💡 Practical example
Sertraline for GAD: the doctor starts at a low dose (50mg), increases it gradually if needed (up to 200mg), and full effect can take 6-8 weeks to appear. Many patients report improved sleep quality and reduced muscle tension before they notice a reduction in worry itself.
Put this knowledge into practice
Balanced Mind brings together the tools you need to manage anxiety day to day.
Works right in your browser — nothing to install.
Start for free